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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
18.18
Human Site:
Y231
Identified Species:
30.77
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
Y231
K
I
Q
F
N
F
P
Y
F
R
S
D
R
D
K
Chimpanzee
Pan troglodytes
XP_514393
802
89426
P190
V
A
A
A
F
G
A
P
I
G
G
T
L
F
S
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
Y231
K
I
Q
F
N
F
P
Y
F
R
S
D
R
D
K
Dog
Lupus familis
XP_535404
889
99260
Y250
K
I
Q
F
N
F
P
Y
F
R
S
D
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
Y231
K
I
Q
F
N
F
P
Y
F
R
S
D
R
D
K
Rat
Rattus norvegicus
P51799
803
88712
I191
F
V
L
V
G
S
V
I
V
A
F
I
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
G238
G
V
L
F
S
V
A
G
G
L
F
V
G
K
E
Chicken
Gallus gallus
XP_417644
868
97172
Y229
K
I
Q
F
N
F
P
Y
F
R
S
D
R
D
K
Frog
Xenopus laevis
Q9W701
689
76782
N77
F
T
V
S
K
M
L
N
A
H
R
W
L
Q
Q
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
R229
R
F
H
F
P
Y
F
R
S
D
R
D
K
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
V191
G
A
I
L
V
S
Y
V
E
P
V
A
A
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
A149
H
S
G
A
I
V
G
A
G
I
P
Q
F
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
I180
I
G
K
I
F
G
S
I
G
S
V
G
G
G
L
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L167
I
F
M
L
L
S
V
L
F
A
L
I
S
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
6.6
100
0
13.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
100
6.6
N.A.
26.6
100
6.6
33.3
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
15
0
0
15
8
8
15
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
43
0
36
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% E
% Phe:
15
15
0
50
15
36
8
0
43
0
15
0
8
8
0
% F
% Gly:
15
8
8
0
8
15
8
8
22
8
8
8
15
15
0
% G
% His:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
15
36
8
8
8
0
0
15
8
8
0
15
0
0
0
% I
% Lys:
36
0
8
0
8
0
0
0
0
0
0
0
8
8
36
% K
% Leu:
0
0
15
15
8
0
8
8
0
8
8
0
15
0
15
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
36
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
36
8
0
8
8
0
0
8
0
% P
% Gln:
0
0
36
0
0
0
0
0
0
0
0
8
0
15
8
% Q
% Arg:
8
0
0
0
0
0
0
8
0
36
15
0
36
8
0
% R
% Ser:
0
8
0
8
8
22
8
0
8
8
36
0
8
0
22
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
8
15
8
8
8
15
15
8
8
0
15
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _